Discover the ultimate in luxury and hospitality when you book a stay with AmericanHotels.co's list of luxury hotels in Wesley Chapel , FL! Whether you're looking for a weekend away or a longer stay, we have you covered. Our hotel listings are conveniently located near some of the city's top-rated attractions such as Busch Gardens Tampa Bay, The Shops at Wiregrass, Wesley Chapel District Park , ZooTampa at Lowry Park, The Florida Aquarium, and Hillsborough River State Park . Plus if you need an immediate spot to crash after a long day exploring the area? Try our "hotels near me" search feature on American Hotels which makes quick and easy booking ideal for those last-minute trips! Book a stay on AmericanHotels.co today and get excitement and big savings out of your dream vacation in Florida!