109 Matthews Lane, Sikeston
The Comfort Inn & Suites Sikeston I-55 hotel offers a convenient Interstate location walking distance from the VF Factory Outlet mall.
2582 North Westwood Boulevard, Sikeston
Comfort Inn Poplar Bluff North is located in Poplar Bluff and features an outdoor pool and a fitness facility. The facility offers complimentary WiFi and is completely smoke-free.
5135 Cairo Road, Sikeston
The Comfort Inn Paducah I-24 hotel is conveniently located near numerous local attractions.
2403 Black Diamond Drive, Sikeston
The Comfort Inn hotel in southern Illinois is conveniently located near a variety of local attractions, including Rent One Park and the Illinois Center Mall. Additionally, this Marion, IL hotel is near Crab Orchard Wildlife and Kokopelli Golf.
1510 East Main Street, Sikeston
The 100 percent non-smoking Comfort Inn & Suites hotel is conveniently located near several area attractions and local points of interest. The surrounding area features outdoor recreational activities like golf; several public courses are nearby.
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This hotel chain's properties are located in the heart of the city, so you'll be close to all the action. No matter what brings you to town, we have the perfect hotel for you. Our selection of Comfort Inns includes business hotels, luxury hotels, and everything in between.
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Save up to 33% on your Comfort Inns stay—reward points for all bookings at Comfort Inns hotels in Sikeston, MO.