Welcome to AmericanHotels.co's luxury hotel listings for Hyannis , MA, USA: the premier destination for an unforgettable vacation filled with history, culture and adventure! We offer a selection of 3+ luxurious hotels in this lovely seaport town, including everything from grand hotels to cozy resorts and convenient apartments. Stay near the city's top attractions, like the John F. Kennedy Memorial, Joseph P. Kennedy House and John F. Kennedy Hyannis Museum; or take in some of the area's unique sights such as Cape Cod Maritime Museum, Veterans Memorial Park and Cape Codder Water Park . No matter what you're looking for in your stay in Hyannis, you can find it here on AmericanHotels.co! Book your accommodation with us now and save big on stays!