Welcome to AmericanHotels.co's luxurious hotel listings for Florence, SC, USA! Our selection of 3+ luxury hotels offers visitors a range of options including hotels, resorts and apartments. Whether you're looking to explore the city's top attractions like the Florence County Museum or Mane Attraction or spend some time in popular areas such as Florence South, Florence Civic Center or Florence North, AmericanHotels.co has something for everyone.

Book your stay with us today and save big on luxurious accommodations! Whether you're looking for an affordable stay close to the city center or a lavish retreat on the outskirts of town, our selection of 3+ luxury hotels provides something for every budget and preference. Enjoy breathtaking views of Lynches River County Park or have an exclusive shopping experience at Pee Dee State Farmers Market – it's all right here at AmericanHotels.co!